Latest Updates

  • Cholera is not convenient, but technologies to control it should be

    David A. Sack, MD

    Professor | Johns Hopkins Bloomberg School of Public Health
    Water collection in east Africa, Photo: Lorenz Von Seidlein

    Water collection in east Africa, Photo: Lorenz Von Seidlein

    I was talking with a health official in Africa this week about an outbreak of cholera in his country.  I asked if vaccine had been considered as a response to the outbreak.  He responded: vaccination would not be possible in this area because it is too remote; the people are farmers living in scattered villages.

  • Understanding Cholera in Nepal

    Nepal is a land-locked country with geographical and socio-cultural proximity to the Gangetic plain and the Bhramputra River basins of West Bengal and Bangladesh. The latter is known as the ‘homeland of cholera’ for its critical relation to six of the seven recent cholera pandemics (1).  Nepal too battles with cholera, and a complex set of factors set the cholera scene in this Himalayan country.

  • Cholera & OCV in the News

    25-Mar-2015: 160,000 people targeted with oral cholera vaccine in Nsanje

    In response to flooding in Nsanje district in Malawi, the Ministry of Health is embarking on a campaign to administer oral cholera vaccine to a targeted 160,000 people at risk for cholera.Settie Kanyanda of the Ministry of Health explained that “Nsanje district is experiencing more cases of cholera as compared to other districts. We feel that the Oral vaccine is a preventive measure to the attacks." This effort is supported by the World Health Organization and the International Vaccine Institute of Korea.  Read the article (25-Mar-2015) or the press release (25-Mar-2014).

  • Vaccine Introduction Cost-Effectiveness (VICE) Calculator

    VICE DALY Sample Graph

    The VICE calculator is a dynamic cost-effectiveness tool to investigate vaccination strategies including mass and targeted vaccination campaigns. The VICE calculator is an Excel file that compares the Disability Adjusted Life Years (DALYs) against the costs and health outcomes of vaccination campaigns. The graph to the left is a sample output graph. A user can enter parameters specific to their context and view the resulting cost-effectiveness output. This calculator can be a useful planning tool. Please also see the accompanying instruction manual to guide you in using VICE. This manual is meant to guide a user in how to use the calculator, taking a step-by-step approach to inputting parameters and interpreting the output. Definitions of the parameters are also provided.

  • Cholera in Africa

    A series of key papers that for the first time describe in depth the epidemiology of cholera in Africa and include findings from on-going laboratory-supported cholera surveillance conducted through the Africhol project and other institutions. This is an excellent overview of the status of cholera in Africa, published as a supplement of the Journal of Infectious Diseases in November 2013. All publications are open source.

  • OCV campaign in Guinea shows vaccination can be done - even during an outbreak

    Denise DeRoeck

    Independent Consultant

    Ever since the first oral cholera vaccines (OCVs) appeared on the global market in 1991, many in the international health community have been skeptical about its use to control an ongoing outbreak. A major argument against reactive cholera vaccination – vaccination in response to an outbreak – was that most countries experiencing cholera outbreaks could not successfully mount vaccination campaigns quickly and that the campaign would divert time, effort and resources from more effective and longer-term measures for controlling cholera, such as improvements in water and sanitation and health education.