Safety of a killed oral cholera vaccine (Shanchol) in pregnant women in Malawi: an observational cohort study
Resource February 2, 2017
Article published in The Lancet on 2-February-2017 by Ali, Mohammad et al.
Pregnancy increases the risk of harmful effects from cholera for both mothers and their fetuses. A killed oral cholera vaccine, Shanchol (Shantha Biotechnics, Hydrabad, India), can protect against the disease for up to 5 years. However, cholera vaccination campaigns have often excluded pregnant women because of insufficient safety data for use during pregnancy. We did an observational cohort study to assess the safety of Shanchol during pregnancy.