Authored by The Coalition for Cholera Prevention and Control (CCPC), this Strategic Framework summarizes existing recommendations and guidelines for preventing and controlling cholera, identifies outdated recommendations and gaps, and recommends new guidelines as suggested by existing research (or identifying areas for further research).
We evaluated the herd protection conferred by an oral cholera vaccine using 2 approaches: cluster design and geographic information system (GIS) design.
BACKGROUND: Zanzibar, in east Africa, has been severely and repeatedly affected by cholera since 1978. We assessed the effectiveness of oral cholera vaccination in high-risk populations in the archipelago to estimate the indirect (herd) protection conferred by the vaccine and direct vaccine effectiveness.